Successful, multiresistant bacterial clones

Successful, multiresistant bacterial clones.

Multilocus sequence typing gives us unparalleled insights into the population biology of bacterial species, including those that cause healthcare-associated and/or community-acquired infections. For many of these species, we now recognize the existence of internationally prevalent clones, which are often resistant to multiple antibiotics.

Editorial: The Global Challenge Posed by the Multiresistant International Clones of Bacterial Pathogens

Multiresistant clones of Salmonella enterica: The importance of dissemination.

Increasing anitmicrobial resistance among foodborne pathogens has prompted calls for the reduction of anitmicrobial use in livestock to prevent future emergence or resistance. In the case of Salmonella enterica, clonal dissemination may play a more critical role in regional changes in antimicrobial resistance in Salmonellae than antimicrobial selection pressure. Multi-resistant Salmonella Typhi...

In vitro antimicrobials activity against endemic Acinetobacter baumannii multiresistant clones.

BACKGROUND Multidrug-resistant strains of Acinetobacter baumannii have been reported increasingly around the world. The administration of an association of antibiotics has been proposed to create an active combination and to prevent the emergence of resistance. METHODOLOGY The activity of colistin, rifampicin, gentamicin, imipenem and their associations was evaluated by means of killing curve...

Impermanence of bacterial clones.

Bacteria reproduce asexually and pass on a single genome copied from the parent, a reproductive mode that assures the clonal descent of progeny; however, a truly clonal bacterial species is extremely rare. The signal of clonality can be interrupted by gene uptake and exchange, initiating homologous recombination that results in the unique sequence of one clone being incorporated into another. B...